第四季开始，艾美奖得主Uzo Aduba饰演新主角，治疗专家Brooke Taylor医生。她将在诊疗中面对多元化的三位病人，与此同时也在与自己的问题作斗争。 Joel Kinnaman将饰演Adam。他是主角医生Brooke时分时合的男友，现在再次出现，让Brooke的生活变得更加复杂。 Anthony Ramos饰演Eladio，病人之一。他是一个有钱人家里成年儿子的家庭护理。 Liza Colón-Zayas饰演Rita。她是Brooke结交已久的知心朋友，给了Brooke很多支持。但Rita在经历了一场改变人生的损失后，也在抗争着自己的心魔。 John Benjamin Hickey饰演Colin。原本是魅力十足的富豪，后来成了一名白领罪犯，最近刚出狱的他需要面对自己生活中方方面面的变化。 Quintessa Swindell饰演Laila。Brooke的客户之一，多疑又叛逆的一名青少年，竭力想要在家人的殷切期盼中找到属于自己的身份。
It is a story of a mistress who comes back for her revenge after enduring all kinds of mistreats from her husband's wedded wife. The resentment between two love rivals is passed on to their descents and grows into a war between two bloodlines. Onnapa is a mistress of a millionaire who owns the biggest flower business in the country. She has endured all kinds of mistreats by her husband's lawful life, Kannika, for years. When their husband dies, Kannika kicked Onnapa out of their home. Onnapa is enraged by the injustice and furious at Kannika. Although more than 30 years have passed, the resentment in Onnapa's heart has never eased off. Now, it is passed on to her daughter and grandchildren. Along with her daughter - Onsalao and her grandsons - Worakorn and Worawet, Onnapa comes back to take her revenge and reclaim things that should have been hers. Onnapa starts a war with Kannika and her descents including Kannika's daughter - Thantawan, and her grandchildren - Mintra, Nonsee, and Iris. Filled with trickery, deceit, and betrayal, how will this war end?
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